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. Author manuscript; available in PMC: 2021 Aug 9.
Published in final edited form as: J Am Coll Cardiol. 2019 Apr 2;73(12):1430–1443. doi: 10.1016/j.jacc.2018.12.072

FIGURE 2. Effect of ExCR on HRQoL and Exercise Capacity at 6 Months: 2-Stage IPD Meta-Analysis.

FIGURE 2

FIGURE 2

The blue circle is centered on the point estimate of the effect of ExCR in each trial, with the horizontal line showing the 95% confidence interval (CI) of this estimate. An arrow to either the left or right shows that the CI extends beyond the area shown in the forest plot. The size of the blue square around the point estimate is proportional to the weight that the individual trial contributes to the meta-analysis. The diamond and vertical red line show the overall estimate of the effect of ExCR in the 2-stage meta-analysis. (A) Minnesota Living with Heart Failure Questionnaire (MLHFQ). (B) All HRQoL measures (standardized score). (C) Peak Vo2, directly reported. (D) 6MWT, directly reported. (E) All exercise capacity measures (standardized score). CBT = cognitive behavioral therapy; ExCR = exercise-based cardiac rehabilitation; HF-ACTION = Exercise Training Program to Improve Clinical Outcomes in Individuals With Congestive Heart Failure; other abbreviations as in Figure 1.