Table 2.
Univariate and Multivariable Analyses for Predictors of Initial Clinical Failure
| Predictor | Univariate | Multivariable | ||
|---|---|---|---|---|
| Odds Ratio (95% CI) | P Value | Odds Ratio (95% CI) | P Value | |
| MTZ MIC ≥1 µg/mL | 2.48 (1.42–4.35) | .001 | 2.44 (1.36–4.36) | .003 |
| Age (per 1-year increase) | 0.99 (.97–1.00) | .007 | 0.98 (.97–.99) | .006 |
| CCI score (per 1-unit increase) | 1.13 (1.01–1.26) | .04 | 1.13 (1.01–1.28) | .04 |
| Severe/fulminant CDI | 1.67 (1.03–2.70) | .04 | 1.61 (.97–2.68) | .07 |
Bolded values indicate those deemed significant with a P value < .05.
Abbreviations: CCI, Charlson Comorbidity Index; CDI, Clostridioides difficile infection; CI, confidence interval; MIC, minimum inhibitory concentration; MTZ, metronidazole.