Table 2.
Percentage parasitaemia and chemosuppresion of P. berghei in infected mice at day 4 post treatment with aqueous and ethanolic leaf and root extracts of Alstonia boonei (curative test)
| Treatments (mg/Kg b. wt/day) |
Parasitaemia (%) | Chemosuppressive activities |
| Baseline | 0.00 ± 0.00a1 | 0.00 ± 0.00a1 |
| Control | 6.53 ± 8.43b13 | 0.00 ± 0.00a1 |
| Artesunate | 7.00 ± 0.58a2 | 88.33 ± 1.76b4 |
| Aqueous leaf (400 mg/kg) | 12.00 ± 1.73a6 | 81.67 ± 2.60b4 |
| Aqueous leaf (600 mg/kg) | 9.33 ± 1.86a4 | 85.66 ± 2.85b4 |
| Aqueous leaf (800 mg/kg) | 8.17 ± 1.01a3 | 87.66 ± 1.45b4 |
| Aqueous Root (400 mg/kg) | 24.00 ± 2.08a12 | 64.73 ± 2.99b2 |
| Aqueous Root (600 mg/kg) | 21.33 ± 4.18a11 | 66.40 ± 3.82b2 |
| Aqueous root (800 mg/kg) | 14.03 ± 2.31a7 | 73.00 ± 2.52b3 |
| Ethanolic leaf (400 mg/kg) | 12.93 ± 2.30a6 | 79.67 ± 3.53b2 |
| Ethanolic leaf (600 mg/kg) | 11.50 ± 3.33a5 | 87.33 ± 1.20b4 |
| Ethanolic leaf (800 mg/kg) | 7.67 ± 1.96a2 | 88.00 ± 3.06b4 |
| Ethanolic Root (400 mg/kg) | 19.60 ± 1.93a10 | 76.33 ± 2.33b3 |
| Ethanolic Root (600 mg/kg) | 18.43 ± 0.81a9 | 77.66 ± 0.88b3 |
| Ethanolic root (800 mg/kg) | 15.33 ± 1.20a8 | 81.67 ± 1.20b4 |
All values expressed as mean ± standard error of mean. Different superscript letters on the same row indicates significance difference (p<0.05) in mean values among treatment indices. Different superscript numerals in the same column indicates significance difference (p<0.05) in mean values of extracts.