Table 4.
Effects of aqueous and ethanolic leaf and root extracts of Alstonia boonei treatments on aspartate aminotransferase of P. berghei infected mice
| Treatments(mg/Kg b. wt/day) | AST (I/U) | ||
| BI | AI | AT | |
| Baseline | 26.97 ± 0.55a3 | 26.97 ± 0.55a1 | 26.97 ± 0.55a2 |
| Control | 27.00 ± 0.58a4 | 35.67 ± 1.45b3 | 50.07 ± 0.58c3 |
| Artesunate | 25.23 ± 0.75a2 | 42.67 ± 0.33c6 | 27.37 ± 1.31b3 |
| Aqueous leaf (400 mg/kg) | 26.83 ± 1.92a3 | 44.00 ± 3.27c8 | 30.77 ± 0.15b5 |
| Aqueous leaf (600 mg/kg) | 27.30 ± 0.30a4 | 43.33 ± 3.71c7 | 29.33 ± 1.86b4 |
| Aqueous leaf (800 mg/kg) | 27.53 ± 0.82a4 | 38.67 ± 3.84b4 | 27.37 ± 1.31a3 |
| Aqueous Root (400 mg/kg) | 26.33 ± 1.20a3 | 41.33 ± 1.86c5 | 39.03 ± 0.58b7 |
| Aqueous Root (600 mg/kg) | 24.83 ± 0.73a1 | 47.00 ± 1.53c10 | 31.23 ± 1.74b6 |
| Aqueous root (800 mg/kg) | 25.70 ± 0.30a2 | 45.33 ± 0.33b9 | 25.93 ± 1.18a1 |
| Ethanolic leaf (400 mg/kg) | 26.00 ± 0.58a3 | 42.37 ± 1.44c2 | 29.00 ± 1.00b4 |
| Ethanolic leaf (600 mg/kg) | 26.00 ± 1.53a3 | 50.00 ± 0.00c12 | 29.00 ± 0.58b4 |
| Ethanolic leaf (800 mg/kg) | 26.07 ± 0.07a3 | 48.00 ± 2.00b11 | 26.33 ± 0.62a2 |
| Ethanolic Root (400 mg/kg) | 25.33 ± 0.33a2 | 34.67 ± 0.67c2 | 30.03 ± 0.55b5 |
| Ethanolic Root (600 mg/kg) | 28.00 ± 0.06a5 | 35.67 ± 0.33c3 | 29.37 ± 0.68b4 |
| Ethanolic root (800 mg/kg) | 26.10 ± 0.10a3 | 34.67 ± 1.20c2 | 29.16 ± 0.44b4 |
All values expressed as mean ± standard error of mean. Different superscript letters on the same row indicates significance difference (p<0.05) in mean values among different treatment periods. Different superscript numerals in the same column indicates significance difference (p<0.05) in mean values of extract. BI: Before Inoculation; AI: After Inoculation; AT: After Treatment.