. 2020 Dec;20(4):1698–1709. doi: 10.4314/ahs.v20i4.21

Table 5.

Effects of aqueous and ethanolic leaf and root extracts of Alstonia boonei treatments on creatinine level of P. berghei infected mice

Treatments(mg/Kg b. wt/day)	Creatinine (mg/dl)
Treatments(mg/Kg b. wt/day)	BI	AI	AT
Baseline	0.73 ± 0.88^b2	0.63 ± 0.09^a1	0.73 ± 0.09^b1
Control	0.67 ± 0.88^a1	2.03 ± 0.34^b3	3.03 ± 0.03^c3
Artesunate	0.77 ± 0.12^a2	2.27 ± 0.29^b3	0.73 ± 0.03^a1
Aqueous leaf (400 mg/kg)	0.80 ± 0.06^a3	1.83 ± 0.12^b2	1.30 ± 0.17^b2
Aqueous leaf (600 mg/kg)	0.66 ± 0.07^a1	2.17 ± 0.32^c3	1.23 ± 0.15^b12
Aqueous leaf (800 mg/kg)	0.83 ± 0.09^a3	2.33 ± 0.29^b3	0.80 ± 0.06^a1
Aqueous Root (400 mg/kg)	0.73 ± 0.03^a2	1.43 ± 0.34^b2	1.06 ± 0.23^b2
Aqueous Root (600 mg/kg)	0.63 ± 0.09^a1	2.00 ± 0.12^b3	0.77 ± 0.12^a1
Aqueous root (800 mg/kg)	0.83 ± 0.09^a3	1.87 ± 0.18^b2	0.70 ± 0.15^a1
Ethanolic leaf (400 mg/kg)	0.77 ± 0.03^a2	2.00 ± 0.15^b3	1.73 ± 0.12^a2
Ethanolic leaf (600 mg/kg)	0.60 ± 0.06^a1	2.23 ± 0.12^c3	1.17 ± 0.09^b2
Ethanolic leaf (800 mg/kg)	0.60 ± 0.00^a1	2.20 ± 0.15^c3	1.00 ± 0.58^b2
Ethanolic Root (400 mg/kg)	0.67 ± 0.03^a1	2.13 ± 0.17^c3	1.00 ± 0.12^b2
Ethanolic Root (600 mg/kg)	0.77 ± 0.09^a2	2.30 ± 0.00^b3	0.87 ± 0.09^a1
Ethanolic root (800 mg/kg)	0.80 ± 0.06^a3	2.20 ± 0.06^b3	0.80 ± 0.06^a1

All values expressed as mean ± standard error of mean. Different superscript letters on the same row indicates significance difference (p<0.05) in mean values among different treatment periods.

Different superscript numerals in the same column indicates significance difference (p<0.05) in mean values of extract. BI: Before Inoculation; AI: After Inoculation; AT: After Treatment.