Table 1.
Baseline Clinical Characteristics and Cardiac Risk Factors in Patients With or Without Cardiotoxicity
| All Patients (N = 74) | Cardiotoxicity (n = 27, 36%) | Noncardiotoxicity (n = 47, 64%) | p Value | |
|---|---|---|---|---|
| Age, yrs | 48.9 ± 11.8 | 49.6 ± 10.7 | 48.5 ± 12.1 | 0.112 |
| Height, cm | 166.9 ± 6.1 | 165.7 ± 6.9 | 167.6 ± 5.7 | 0.201 |
| Weight, kg | 65.6 ± 11.6 | 64.4 ± 10.7 | 66.3 ± 11.9 | 0.197 |
| HR, beats/min | 78.6 ± 11.9 | 79.3 ± 11.1 | 78.2 ± 12.4 | 0.226 |
| SBP, mm Hg | 117.4 ± 9.6 | 118.0 ± 9.1 | 117.1 ± 10.3 | 0.109 |
| DBP, mm Hg | 75.2 ± 7.4 | 74.8 ± 6.3 | 75.4 ± 8.1 | 0.318 |
| Women | 33 | 11 | 22 | 0.092 |
| Men | 41 | 16 | 25 | 0.114 |
| Diabetes mellitus | 5 (7) | 2 (7) | 3 (6) | 0.252 |
| Smoker | 20 (27) | 8 (29) | 12 (25) | 0.102 |
| Cumulative anthracycline dose, mg/m2 | 358.20 ± 69.04 | 367.30 ± 63.10 | 352.90 ± 71.14 | 0.097 |
Values are mean ± SD, n, or n (%). The p values compare cardiotoxicity with noncardiotoxicity.
DBP = diastolic blood pressure; HR = heart rate; SBP = systolic blood pressure.