Table 2.
Spectrum of Clonal Plasma Cell Disorders
| MGUS | Asymptomatic Myeloma | Symptomatic Myeloma | AL Amyloidosis | |
|---|---|---|---|---|
| How common is it?∗ | +++++++ | +++++ | +++ | + | 
| Typical clonal plasma cell percentage | <10% | 10%-60% | >10% | Any | 
| Typical concentration of paraprotein on SPIE/UPIE/serum FLC | Low | Moderate | High | Any | 
| Treatment required? | No | No | Yes | Yes | 
MGUS = monoclonal gammopathy of undetermined significance; other abbreviations as in Table 1.
More + refers to being more common.