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. 2021 Apr 20;3(2):173–190. doi: 10.1016/j.jaccao.2021.03.001

Table 3.

Direct Oral Anticoagulants Dosing Regimens for Prophylaxis and Treatment of Venous Thromboembolism

Drug Prophylaxis Treatment
Apixaban 2.5 mg orally twice daily 10 mg twice daily for the first 7 days, followed by 5 mg twice daily
Rivaroxaban 10 mg orally once daily 15 mg orally every 12 h for 21 days, followed by 20 mg once daily
Edoxaban Not applicable 60 mg daily after at least 5 days of low-molecular-weight heparin