Table 6.
Univariable |
Multivariable∗ |
|||
---|---|---|---|---|
Hazard Ratio (95% CI) | p Value | Hazard Ratio (95% CI) | p Value | |
Age at start | 0.98 (0.95–1.02) | 0.44 | ||
Female | 0.92 (0.45–1.89) | 0.82 | ||
ICI | 1.18 (0.57–2.43) | 0.66 | 0.63 (0.29–1.35) | 0.23 |
Nivolumab | 1.16 (0.54–2.51) | 0.70 | ||
Pembrolizumab | 1.14 (0.47–2.75) | 0.77 | ||
Atezolizumab | 0.71 (0.17–3.03) | 0.64 | ||
Elevated troponin I (>0.01 ng/ml) | 9.82 (4.91–19.66) | <0.001 | 7.27 (2.72–19.43) | <0.001 |
Initial troponin (in ng/ml) | 1.01 (0.99–1.02) | 0.54 | ||
Peak troponin (in ng/ml) | 1.01 (0.99–1.02) | 0.20 | ||
Elevated BNP (>100 pg/ml) | 5.14 (2.36–11.20) | <0.001 | 2.65 (1.01–6.92) | 0.047 |
CI = confidence interval; other abbreviations as in Table 2.
Adjusted for ICI, elevated serum troponin I, and elevated serum BNP categorical variables.