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. Author manuscript; available in PMC: 2022 Aug 10.
Published in final edited form as: J Am Coll Cardiol. 2021 Aug 10;78(6):562–571. doi: 10.1016/j.jacc.2021.05.041

Table 2:

Pre-MRI vascular risk factor exposure relationship with asymptomatic intracranial large artery stenosis (ordinal categories).

Model 1 Model 2 Model 3
Odds ratio, 95% confidence intervals
Age (in years) at MRI 1.05, 1.03-1.06s 1.05, 1.03-1.06 1.02, 1.01-1.04
Male sex 1.08, 0.84-1.40 1.18, 0.91-1.53 0.87, 0.67-1.14
Ethnicity
    NH white Reference group Reference group Reference group
NH black 1.11, 0.75-1.68 1.03, 0.68-1.58 1.00, 0.67-1.451
Hispanic 1.03, 0.69-1.52 0.89, 0.60-1.34 1.04, 0.72-1.52
High school completed (yes/no) 0.85, 0.62-1.15 0.86, 0.63-1.18 1.12, 0.84-1.49
Visits to PMD during pre MRI follow up period 1.06, 0.55-2.04 1.00, 0.51-1.96 0.77, 0.38-1.57
Hypertension (yes/no) at MRI 1.74, 1.22-2.49
SBP (per each 5 mmHg) 1.03, 0.99-1.07
DBP (per each 5 mmHg) 0.98, 0.91-1.06
Number of antihypertensives at MRI 1.03, 0.88-1.22
Hypertension duration (in years) at MRI 1.01, 1.001-1.025
Diabetes(yes/no) at MRI 1.60, 1.21-2.13
Fasting glucose (per each 5 mg/dL) 1.00, 0.98-1.01
Number of glucose-lowering drugs at MRI 1.64, 1.24-2.15
Diabetes duration (in years) 0.99, 0.96-1.02
Hypercholesterolemia (yes/no) at MRI 2.03, 1.19-3.46
LDL (per each 5 mg/dL) 1.01, 1.00-1.03
HDL (per each 5 mg/dL) 0.96, 0.92-0.99
Triglycerides (mg/dL) 1.01, 0.99-1.02
Number of cholesterol-lowering drugs at MRI 1.02, 0.81-1.34
Smoking (yes/no) at MRI 1.21, 0.81-1.82
Smoking duration (in years) 1.01, 1.00-1.01
Packs per day (pear each 5) 0.95, 0.76-1.19

Statistical note: Model included all variables with valid beta estimate in each column.

Abbreviations: SD, standard deviation; NH, non-Hispanic; PMD, primary care doctor; SBP, systolic blood pressure; DBP, diastolic blood pressure; mg, milligrams; dL, deciliter; LDL, low density lipoprotein; HDL, high density lipoprotein.