Table 4:
Risk of vascular events per intracranial large artery stenosis category in adjusted models.
| Any death |
Vascular death |
Myocardial Infarction |
Ischemic stroke |
Cardioembolic Stroke |
Intracranial small or large disease |
Stroke, myocardial infarction, or vascular death |
|
|---|---|---|---|---|---|---|---|
| Number of events |
454 | 200 | 61 | 122 | 39 | 36 | 324 |
| HR, 95% CI |
HR, 95% CI |
HR, 95% CI | HR, 95% CI | HR, 95% CI | HR, 95% CI | HR, 95% CI | |
| Cox proportional models | |||||||
| No stenosis | Referent group | ||||||
| <50% stenosis | 0.95, 0.77-1.17 |
0.90, 0.65-1.25 |
1.22, 0.71-2.09 |
1.06, 0.69-1.62 |
0.92, 0.75-1.13 |
1.40, 0.67-2.89 |
1.04, 0.81-1.32 |
| 50-70% stenosis | 1.24, 0.77-1.99 |
1.53, 0.81-2.89 |
0.49, 0.07-3.69 |
1.59, 0.65-3.90 |
1.05, 0.65-1.69 |
2.10, 0.45-9.68 |
1.09, 0.62-1.92 |
| >70% stenosis | 1.31, 0.91-1.90 |
1.60, 0.96-2.65 |
1.22, 0.40-3.56 |
1.50, 0.69-3.26 |
1.22, 0.85-1.76 |
3.60, 1.17-11.14 |
1.52, 1.003-2.31 |
| Fine & Gray competing risk models | |||||||
| No stenosis | Referent group | ||||||
| <50% stenosis | - | 0.8, 0.6-1.1 |
1.2, 0.6-2.2 |
1.0, 0.7-1.6 |
0.9, 0.5-1.9 |
1.4, 0.6-2.8 |
1.0, 0.8-1.3 |
| 50-70% stenosis | - | 1.7, 0.8-3.4 |
0.6, 0.1-5.0 |
2.1, 0.8-5.1 |
2.4, 0.6-9.3 |
2.4, 0.5-10.7 |
1.3, 0.7-2.3 |
| >70% stenosis | - | 1.4, 0.8-2.4 |
0.8, 0.2-4.1 |
1.8, 0.8-3.7 |
1.1, 0.3-3.9 |
3.9, 1.2-12.5 |
1.7, 1.1-2.5 |
Abbreviations:
Model adjusted for age, sex, ethnicity, prevalent risk factors at the time of MRI (hypertension, diabetes, dyslipidemia and smoking), self-reported medications to treat vascular risks at the time of MRI, use of oral antiplatelets or anticoagulants at the time of MRI, established PMD care at the time of MRI.