Table 5:

Role of vascular risks in post MRI vascular events in NOMAS participants with asymptomatic intracranial large artery stenosis

		Vascular death	Myocardial infarction	Ischemic stroke
		HR, 95% CI	HR, 95% CI	HR, 95% CI
Age (in years)		1.1, 1.1-1.1	1.0, 1.0-1.0	1.1, 1.1-1.1
Male sex		1.1, 0.8-1.5	1.1, 0.6-2.0	1.2, 0.8-1.8
Ethnicity
	NH white	Reference	Reference	Reference
	NH black	0.8, 0.5-1.2	0.8, 0.3-1.9	0.9, 0.5-1.7
	Hispanic	0.6, 0.4-0.8	0.6, 0.3-1.1	1.2, 0.7-2.0
PMD visits post MRI		0.3, 0.2-0.50	0.2, 0.1-0.60	0.6, 0.2-1.5
Antiplatelets exposure (in years) post MRI		1.0, 0.7-1.3	0.6, 0.3-1.2	1.1, 0.7-1.6
Anticoagulant exposure (in years) post MRI		1.4, 0.6-3.0	2.4, 0.6-9.5	3.4, 1.7-7.1
Hypertension at MRI or after		1.2, 0.8-2.0	1.4, 0.4-4.1	0.9, 0.5-1.8
	Antihypertensive use at the time of MRI	1.0, 0.7-1.5	1.7, 0.7-4.1	0.8, 0.5-1.5
	Hypertension duration (in years) prior to MRI	1.0, 1.0-1.0	1.0, 1.0-1.0	1.0, 1.0-1.0
Diabetes at MRI or after		1.0, 0.5-1.8	2.1, 0.9-5.1	0.5, 0.2-1.0
	Hypoglycemic at the time of MRI	1.6, 0.8-3.2	0.6, 0.2-1.7	3.4, 1.5-7.8
	Diabetes duration (in years) prior to MRI	1.0, 1.0-1.0	1.0, 1.0-1.1	1.0, 0.9-1.0
Hypercholesterolemia at MRI or after		0.6, 0.4-1.1	0.9, 0.3-2.8	1.4, 0.6-3.5
	Lipid-lowering drugs at the time of MRI	1.2, 0.9-1.7	1.4, 0.8-2.7	1.1, 0.7-1.8
Smoking at the time of MRI		0.8, 0.5-1.5	0.4, 0.1-1.3	1.9, 0.9-4.1
	Smoking duration (in years) prior to MRI	1.0, 1.0-1.0	1.0, 1.0-1.0	1.0, 1.0-1.0

Statistical note: Model adjusted for all variables listed in column one of this table. Estimates calculated with Fine and Gray regressions.

Abbreviations: SD, standard deviation; NH, non-Hispanic; PMD, primary medical doctor; SBP, systolic blood pressure; DBP, diastolic blood pressure; mg, milligrams; dL, deciliter; LDL, low density lipoprotein; HDL, high density lipoprotein.