Central Illustration.

Typical Cardiovascular Effects of Classes of Cancer Therapy With Suggested Cardiovascular Magnetic Resonance Imaging Protocols

The typical cardiovascular effects of various classes of cancer therapy, together with suggested cardiovascular magnetic resonance (CMR) imaging protocols and key metrics provided by each sequence. “Recommended” and “aspirational” CMR imaging sequences to characterize the respective pathologies are suggested. For specific data on the timing and incidence of toxicity, please see relevant literature (1,66,72,80,81,91,110, 111, 112, 113). ∗Contrast administration may not necessarily be required for serial evaluation of left ventricular function. ACS = acute coronary syndrome; CAD = coronary artery disease; ECV = extracellular volume fraction; HER2+ = human epidermal growth factor receptor; LV = left ventricular; TKI = tyrosine kinase inhibitor; VEGF = vascular endothelial growth factor.