Figure 2.

rRIC Inhibited Doxorubicin-Induced Alteration of Circulating Markers of Multiorgan Dysfunction

Circulating multiorgan markers were tested with commercially available assay kits. The tested markers include creatinine kinase (CK) (A), troponin I (B), aspartate aminotransferase (AST) (C), and blood urea nitrogen (BUN) (D). *p < 0.05 and **p < 0.01 versus vehicle, whereas †p < 0.05 versus doxorubicin alone. n = 8 in each of the groups (vehicle, doxorubicin, doxorubicin + rRIC). Abbreviations as in Figure 1.