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. 2020 Mar 17;2(1):41–52. doi: 10.1016/j.jaccao.2020.01.005

Central Illustration.

Central Illustration

Effects of Remote Ischemic Conditioning on Doxorubicin-Induced Cardiotoxicity

Injection of doxorubicin caused decline of cardiac function, increased cardiac fibrosis, decreased myocyte cross-section area, and increased cardiomyocyte apoptosis. Remote ischemic conditioning abrogated doxorubicin-induced cardiotoxicity. rRIC = repeated remote ischemic conditioning.