Table 7.
Levels of Stool Microbiota
| Phylum | Microbiota (CFU/g stool) | Untransformed Data | Log Transformed Data | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | Day 10 | Baseline | Day 10 | Geometric mean % Δ | P valuea | Cohen’s d | ||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | |||||
| Actinobacteria | Bifidobacterium spp. | 1.6E+09 | 1.9E+09 | 3.0E+09 | 3.3E+09 | 20.1 | 2.3 | 21.3 | 1.1 | 222.9% | .106 | 0.52 |
| Bifidobacterium longum | 1.1E+08 | 1.4E+08 | 9.3E+07 | 1.7E+08 | 17.3 | 2.2 | 17.6 | 1.1 | 43.6% | .567 | 0.16 | |
| Collinsella aerofaciens | 9.3E+08 | 9.4E+08 | 1.2E+09 | 1.2E+09 | 19.7 | 2.0 | 20.0 | 2.4 | 34.0% | .547 | 0.15 | |
| Bacteroidetes | Bacteroides-Prevotella group | 9.4E+08 | 5.4E+08 | 8.4E+09 | 6.9E+08 | 20.5 | 0.6 | 20.7 | 0.7 | 25.8% | .283 | 0.36 |
| Bacteroides vulgatus | 5.9E+09 | 4.8E+09 | 8.4E+09 | 7.7E+09 | 22.2 | 0.8 | 22.4 | 1.1 | 19.7% | .692 | 0.22 | |
| Barnesiella spp. | 9.9E+07 | 1.7E+08 | 1.1E+08 | 1.7E+08 | 15.9 | 2.7 | 16.3 | 2.8 | 48.9% | .519 | 0.15 | |
| Odoribacter spp. | 1.6E+08 | 1.5E+08 | 1.5E+08 | 1.3E+08 | 17.2 | 3.3 | 17.9 | 2.0 | 101.2% | .188 | 0.21 | |
| Prevotella spp. | 2.1E+07 | 2.1E+07 | 2.2E+07 | 1.5E+07 | 16.4 | 1.1 | 16.6 | 0.9 | 27.2% | .632 | 0.22 | |
| Euryarchaeota | Methanobrevibacter smithii | 7.1E+07 | 1.3E+08 | 3.9E+07 | 8.1E+07 | 14.0 | 3.4 | 14.6 | 2.9 | 71.0% | .398 | 0.16 |
| Firmicutes | Anaerotruncus colihominis | 1.9E+07 | 2.0E+07 | 1.9E+07 | 1.8E+07 | 16.1 | 1.4 | 16.4 | 0.9 | 43.2% | .311 | 0.26 |
| Butyrivibrio crossotus | 1.1E+05 | 1.0E+05 | 1.5E+05 | 2.7E+05 | 10.5 | 2.3 | 10.0 | 2.6 | -35.7% | .762 | -0.20 | |
| Clostridium spp. | 5.8E+09 | 9.4E+09 | 5.7E+09 | 6.7E+09 | 21.2 | 1.9 | 21.9 | 1.1 | 99.7% | .262 | 0.36 | |
| Coprococcus eutactus | 8.5E+06 | 8.9E+06 | 1.6E+07 | 1.3E+07 | 14.9 | 2.0 | 16.2 | 0.9 | 268.2% | .110 | 0.67 | |
| Faecalibacterium prausnitzii | 2.1E+09 | 2.4E+09 | 7.5E+09 | 6.4E+09 | 20.6 | 2.0 | 22.4 | 0.9 | 504.4% | .025b | 0.91 | |
| Lactobacillus spp. | 1.4E+09 | 1.2E+09 | 9.6E+09 | 7.3E+09 | 20.4 | 1.6 | 22.7 | 0.7 | 924.0% | .003b | 1.45 | |
| Pseudoflavonifractor spp. | 2.5E+08 | 2.2E+08 | 2.7E+08 | 1.9E+08 | 18.7 | 1.5 | 19.0 | 1.3 | 33.7% | .586 | 0.20 | |
| Roseburia spp. | 3.0E+09 | 2.0E+09 | 4.2E+09 | 2.4E+09 | 21.5 | 1.0 | 22.0 | 0.5 | 67.6% | .221 | -0.54 | |
| Ruminococcus spp. | 1.6E+08 | 1.3E+08 | 5.8E+08 | 7.3E+08 | 18.4 | 1.3 | 19.5 | 1.3 | 174.5% | .034 | 0.80 | |
| Veillonella spp. | 9.8E+06 | 8.2E+06 | 1.9E+07 | 1.6E+07 | 15.4 | 1.6 | 16.3 | 1.2 | 135.0% | .220 | 0.52 | |
| Fusobacteria | Fusobacterium spp. | 8.6E+04 | 1.3E+05 | 9.5E+04 | 9.3E+04 | 9.5 | 2.6 | 11.0 | 1.1 | 342.7% | .102 | 0.57 |
| Proteobacteria | Desulfovibrio piger | 1.2E+07 | 3.3E+07 | 8.5E+07 | 2.4E+07 | 12.4 | 3.2 | 10.6 | 3.1 | -82.4% | .028 | -0.54 |
| Escherichia coli | 5.5E+07 | 6.1E+07 | 3.6E+08 | 8.7E+08 | 17.0 | 1.6 | 17.5 | 2.2 | 61.0% | .478 | 0.29 | |
| Oxalobacter formigenes | 7.8E+06 | 9.1E+07 | 8.2E+06 | 8.2E+06 | 15.3 | 1.1 | 15.6 | 0.8 | 35.7% | .397 | 0.27 | |
| Verrucomicrobia | Akkermansia muciniphila | 1.1E+07 | 1.7E+07 | 2.0E+07 | 1.9E+07 | 13.8 | 3.1 | 16.0 | 1.7 | 805.2% | .045b | 0.71 |
aP values calculated using paired t test.
bP values confirmed with a Wilcoxon signed rank test (P < .05).
Abbreviations: Δ, change; CFU, colony-forming units; g, gram; SD, standard deviation; spp., species.