Table 1.

List of disease that treated by LQC.

Disease	Pathogen	Symptoms	Inflammatory cytokines	Symptom improvement	Adverse effect	Ref
COVID-19	SARS-COV-2	Fever, cough, fatigue, headache, dizziness, vomiting, ARDS, MOF	Decrease	Yes	Mild	[10], [11], [12], [13], [17], [20], [21], [22], [27], [28]
SARS	SARS-COV	Fever, headache, dyspnea, sore throat，ARDS	Decrease	Yes	Mild	[33], [34], [35], [39], [40]
H1N1	Type A Influenza virus	Fever, headache, dizziness, fatigue, rhinorrhea	Decrease	Yes	Mild	[47], [48], [49]
H7N9	Type A Influenza virus	Fever, headache, dizziness, fatigue, rhinorrhea	Decrease	Yes	Mild	[47], [48], [49]
Chronic rhinosinusitis	Acute rhinosinusitis	nasal obstruction, nasal discharge, facial pain, smell reduction or loss	Decrease	Yes	Minor	[50], [51], [52]
Tonsillitis	Streptococcus/ staphylococcus	Fever, alleviate tonsil enlargement, throat pain	Decrease	Yes	NO	[53]
Hand-foot-and-mouth disease	Coxsachie (Cox A16) virus /human enterovirus 71 (EV 71)	Fever, dental ulcer, rash, herpes	Decrease	Yes	Mild	[54]