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. 2020 Nov 19;10(3):175–181. doi: 10.1097/XCE.0000000000000240

Table 5.

Biomarkers of left ventricular diastolic function

NRI IDI AUC
Event Non-event Event Non-event
CT-1 −0.353 (−0.500, 0.533) 0.333 (−0.647, 0.745) 0.005 (−0.016, 0.044) −0.002 (−0.026, 0.082) 0.5231 (0.6031)
BNP −0.294 (−0.383, 0.389) −0.429 (−0.631, 0.625) −0.014 (−0.015, 0.053) −0.033 (−0.040, 0.090) 0.7777 (0.1603)
IGFBP-7 0.000 (−0.351, 0.375) 0.333 (−0.600, 0.571) −0.002 (−0.014, 0.047) −0.004 (−0.026, 0.080) 0.5602 (0.3632)
TGF-β1 0.163 (0.013, 0.321) 0.231 (0.003, 0.343) 0.278 (0.013, 0.311) 0.211 (0.07, 0.381) 0.381 (0.231)

AUC, area under the curve; BNP, brain natriuretic peptide; CT-1, plasma cardiotrophin; IDI, integrated discrimination index; IGFBP-7, human insulin-like growth factor binding protein-7; NRI; net reclassification index; TGF-β1, human transforming growth factors β1.