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. 2021 Aug 10;142:112023. doi: 10.1016/j.biopha.2021.112023

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© 2021 Published by Elsevier Masson SAS.

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Fig. 1 — Schematic representation of the Methylene blue accompanied by supplemental oxygen. The methylene blue undergoes reduction by nicotinamide adenine dinucleotide phosphate (NADPH) to produce leucomethylene blue (leucoMB). Note: Fe⁺²: Ferrous; Fe⁺³: Ferric; RBC: Red blood cells; NADPH: Nicotinamide adenine dinucleotide phosphate; NADP⁺: Nicotinamide adenine dinucleotide.