Skip to main content
. 2021 Aug 10;69:101445. doi: 10.1016/j.trim.2021.101445

Table 3.

Treatment choice and complications.

Patient

1 2 3 4 5 6 7
The severity of the disease Asymptomatic Mild Moderate Severe Severe Critical Critical
IS adjustment
MMF reduction or interruption No No I R I R I
FK506 reduction or interruption No No I R I R I
Treatment
Antivirus therapy Yes Yes Yes Yes Yes Yes Yes
Arbidol No Yes Yes Yes Yes Yes Yes
Lopinavir/ritonavir No No Yes No No No Yes
Chloroquine phosphate No No Yes No No No No
IVIG/days No Yes/7d Yes/7d Yes/5d Yes/3d Yes/7d Yes/14d
MP/days No No Yes/10d Yes/3d Yes/3d No Yes/18d
Other complications and support
 Septic shock No No No No No No No
 ICU admission No No No No No Yes Yes
 AKI No No Yes No No Yes Yes
 Rejection No No Yes No No No Yes
 Acute cardiac injury No No No No No Yes Yes
 ARDS No No No Yes Yes Yes Yes
Life support
 Initiation of invasive ventilation No No No No No No Yes
 Initiation of noninvasive ventilation No No No No No Yes Yes
 Initiation of renal replacement therapy No No No No No Yes Yes
Outcome Discharge Discharge Discharge Discharge Discharge Discharge Death

Note: IS = immunosuppressant; MPA = mycophenolic acid; FK506 = tacrolimus; IVIG = intravenous immunoglobulin; MP = methylprednisolone; ICU = intensive care unit, AKI = acute kidney injury; ARDS = acute respiratory distress syndrome.