Table 3.
Patient |
|||||||
---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | |
The severity of the disease | Asymptomatic | Mild | Moderate | Severe | Severe | Critical | Critical |
IS adjustment | |||||||
MMF reduction or interruption | No | No | I | R | I | R | I |
FK506 reduction or interruption | No | No | I | R | I | R | I |
Treatment | |||||||
Antivirus therapy | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
Arbidol | No | Yes | Yes | Yes | Yes | Yes | Yes |
Lopinavir/ritonavir | No | No | Yes | No | No | No | Yes |
Chloroquine phosphate | No | No | Yes | No | No | No | No |
IVIG/days | No | Yes/7d | Yes/7d | Yes/5d | Yes/3d | Yes/7d | Yes/14d |
MP/days | No | No | Yes/10d | Yes/3d | Yes/3d | No | Yes/18d |
Other complications and support | |||||||
Septic shock | No | No | No | No | No | No | No |
ICU admission | No | No | No | No | No | Yes | Yes |
AKI | No | No | Yes | No | No | Yes | Yes |
Rejection | No | No | Yes | No | No | No | Yes |
Acute cardiac injury | No | No | No | No | No | Yes | Yes |
ARDS | No | No | No | Yes | Yes | Yes | Yes |
Life support | |||||||
Initiation of invasive ventilation | No | No | No | No | No | No | Yes |
Initiation of noninvasive ventilation | No | No | No | No | No | Yes | Yes |
Initiation of renal replacement therapy | No | No | No | No | No | Yes | Yes |
Outcome | Discharge | Discharge | Discharge | Discharge | Discharge | Discharge | Death |
Note: IS = immunosuppressant; MPA = mycophenolic acid; FK506 = tacrolimus; IVIG = intravenous immunoglobulin; MP = methylprednisolone; ICU = intensive care unit, AKI = acute kidney injury; ARDS = acute respiratory distress syndrome.