Table 2.
Comparison of redox biomarkers in healthy controls and patients with colorectal cancer before and after surgery.
| Markers | Healthy control | Before surgery | p value | Healthy control | After surgery | p value |
|---|---|---|---|---|---|---|
| AGE (F %) | 44.62 ± 7.08 | 72.49 ± 4.7 | <0.001 | 44.62 ± 7.08 | 67.93 ± 8.8 | <0.001 |
| AOPP (μmol/L) | 129.1 ± 12.1 | 137.64 ± 21.9 | 0.014 | 129.1 ± 12.1 | 119.08 ± 33.1 | 0.035 |
| MDA (μM/L) | 2.74 ± 0.37 | 3.56 ± 0.30 | <0.001 | 2.74 ± 0.37 | 3.05 ± 0.33 | <0.001 |
| ox-LDL (mU/L) | 14.43 ± 1.17 | 19.78 ± 0.97 | <0.001 | 14.43 ± 1.17 | 16.94 ± 1.02 | <0.001 |
| FRAP (μmol/L) | 1000 ± 213.9 | 1097.5 ± 156 | 0.013 | 1000 ± 213.9 | 1239.3 ± 290 | <0.001 |
| CAT (U/mL) | 2.48 ± 0.36 | 2.34 ± 0.34 | 0.049 | 2.48 ± 0.36 | 2.63 ± 0.38 | 0.045 |
| GPx (U/mL) | 90.1 ± 7 | 102.37 ± 6.58 | <0.001 | 90.1 ± 7 | 108.03 ± 6.95 | <0.001 |
| SOD (U/mL) | 4.34 ± 0.35 | 5.13 ± 0.39 | <0.001 | 4.34 ± 0.35 | 5.53 ± 0.31 | <0.001 |
Data is presented as mean ± SD. AGE: advanced glycation end product; AOPP: advanced oxidation protein products; CAT: catalase; FRAP: ferric reducing ability of plasma; GPx: glutathione peroxidase; MDA: malondialdehyde; ox-LDL: oxidized low density lipoprotein; SOD: superoxide dismutase.