Table 2.
Demographic and clinical characteristics of patients with obesity and matched controls: ulcerative colitis.
| Ulcerative colitis (BMI > 30) | Ulcerative colitis (BMI < 30) | P-value | |
|---|---|---|---|
| No. of patients | 27 | 108 | |
| Median BMI at diagnosis (range) | 31.3 (30.3–37.1) | 22.9 (14.0–29.3) | |
| Male (%) | 21 (77.8) | 84 (77.8) | 1.000 |
| Median age at diagnosis (range), years | 42 (16–69) | 42 (16–71) | 0.974 |
| Median interval from onset to diagnosis (range), months | 2.1 (0–24.7) | 2.9 (0–63.8) | 0.483 |
| Mean follow-up after diagnosis of IBD (months) | 71.0 ± 34.6 | 62.1 ± 33.1 | 0.219 |
| Smoking status at diagnosis (%) | 0.648 | ||
| Current smokers | 7 (25.9) | 23 (21.3) | |
| Ex-smokers | 7 (25.9) | 38 (35.2) | |
| Never-smokers | 13 (48.1) | 47 (43.5) | |
| UC extent (at diagnosis) | 0.883 | ||
| Proctitis | 12 (44.4) | 52 (48.1) | |
| Left-sided colitis | 8 (29.6) | 27 (25.0) | |
| Extensive colitis | 7 (25.9) | 29 (26.9) | |
| UC extent (worst ever) | 0.467 | ||
| Proctitis | 10 (37.0) | 42 (38.9) | |
| Left-sided colitis | 10 (37.0) | 28 (25.9) | |
| Extensive colitis | 7 (25.9) | 38 (35.2) | |
| Medication history | |||
| Steroids | 8 (29.6) | 49 (45.4) | 0.139 |
| Immunomodulators | 3 (11.1) | 28 (25.9) | 0.102 |
| Anti-tumor necrosis factor therapy | 1 (3.7) | 17 (15.7) | 0.083 |
| Surgical outcomes | |||
| Colectomy | 0 (0.0) | 8 (7.4) | 0.159 |
GI, gastrointestinal, IBD, inflammatory bowel disease, UC, ulcerative colitis, and BMI, body mass index.