Table 3.
Logistic regression of cannabis use before and during pregnancy
| Characteristics | Preconception | Prenatal | ||
|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | |
| Age, years | ||||
| 18–19 | 1.30 (1.05–1.62) | 0.02 | 1.17 (0.88–1.56) | 0.27 |
| 20–24 | 1.08 (0.91–1.19) | 0.23 | 1.17 (0.99–1.37) | 0.09 |
| 25–29 | – | – | ||
| 30–34 | 0.95 (0.83–1.10) | 0.47 | 0.93 (0.78–1.01) | 0.41 |
| 35–39 | 0.96 (0.81–1.16) | 0.74 | 0.88 (0.73–1.03) | 0.33 |
| 40+ | 0.87 (0.62–1.22) | 0.41 | 1.10 (0.52–1.01) | 0.62 |
| Education | ||||
| 12 years or less | – | – | ||
| 13–15 years | 0.89 (0.79–1.00) | 0.052 | 0.88 (0.77–1.02) | 0.096 |
| 16 or more years | 0.70 (0.59–0.82) | < 0.01 | 0.44 (0.34–0.55) | < 0.01 |
| Marital status | ||||
| Married | – | – | ||
| Not married | 2.23 (1.97–2.51) | < 0.01 | 2.29 (1.96–2.67) | < 0.01 |
| Race/ethnicity | ||||
| White non-hispanic | – | – | ||
| Non-hispanic black | 1.98 (1.72–2.27) | < 0.01 | 1.19 (0.99–1.43) | 0.24 |
| Hispanic | 0.58 (0.42–0.79) | < 0.01 | 0.59 (0.41–0.98) | 0.05 |
| Asian | 0.76 (0.55–1.01) | 0.08 | 0.58 (0.29–0.59) | 0.02 |
| AIAN | 2.72 (2.27–3.28) | < 0.01 | 1.24 (0.97–1.56) | 0.07 |
| Other/unknown/mixed | 1.46 (1.27–1.67) | < 0.01 | 1.2 (1.07–1.51) | 0.01 |
| Legalization status in state of residence | ||||
| Residence in a recreational legal state | 2.37 (2.04–2.75) | < 0.01 | 1.51 (1.29–1.79) | < 0.01 |
| Residence in a medical legal state | 3.32 (2.90–3.80) | < 0.01 | 0.90 (0.76–1.06) | 0.21 |
| Residence in a state with no legalization | – | – | ||
| Tobacco use(traditional and e-cigarette) | ||||
| Tobacco use | 3.22 (2.93–3.53) | < 0.01 | 4.50 (4.00–5.00) | < 0.01 |
| No tobacco use | – | – | ||
| Moderate alcohol use before pregnancy | ||||
| No moderate use | – | – | ||
| Moderate alcohol use before pregnancy | 1.91 (1.56–2.38) | < 0.01 | 2.30 (1.81–2.92) | < 0.01 |
| Skipped or unknown | 0.33 (0.28–0.38) | < 0.01 | 0.40 (0.36–0.47) | < 0.01 |
| Kotelchuck index | ||||
| Inadequate | 1.26 (1.09–1.47) | < 0.01 | 1.62 (1.41–1.88) | < 0.01 |
| Intermediate | 1.01 (0.85–1.20) | 0.87 | 1.37 (1.16–1.62) | < 0.01 |
| Adequate | – | Reference | ||
| Adequate plus | 1.00 (0.89–1.19) | 0.91 | 1.03 (0.89–1.20) | 0.67 |
| Parity | ||||
| No previous live births | – | – | ||
| One previous live birth | 0.66 (0.59–0.74) | < 0.01 | 0.86 (0.79–0.99) | 0.05 |
| Two previous live births | 0.60 (0.52–0.71) | < 0.01 | 0.82 (0.68–0.97) | 0.04 |
| Three or more previous live births | 0.58 (0.49–0.70) | < 0.01 | 0.85 (0.68–1.05) | 0.13 |
Moderate alcohol use prior to pregnancy defined as consuming > seven drinks in a week
AIAN american indian, alaskan native, PI pacific islander, CI confidence interval
α = 0.05