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. 2021 Feb 2;259(8):2181–2192. doi: 10.1007/s00417-020-05048-1

Table 2.

Subgroup analysis for the absence of fluid, interval extension and retention rate

12 months 24 months
n kS % p n kS % p
Absence of fluid
  Ranibizumab 0.5 mg 1062 7 56.3 < 0.001 1081 5 50.0 < 0.001
  Aflibercept 2.0 mg 442 5 64.5 1938 9 52.7
  Brolucizumab 6.0 mg 730 2 71.5 646 2 75.7
Interval extension (12 weeks)
  Ranibizumab 0.5 mg 943 6 28.6 < 0.001 1339 7 34.2 < 0.001
  Aflibercept 2.0 mg 770 7 34.2 2360 13 47.7
  Brolucizumab 6.0 mg 730 2 53.3 646 2 41.7
Retention rate
  Ranibizumab 0.5 mg 943 6 90.5 0.69 1339 7 81.6 < 0.001
  Aflibercept 2.0 mg 60 2 91.0 2266 12 81.7
  Brolucizumab 6.0 mg 730 2 91.6 646 2 88.6

kS, number of samples included in the analysis

The p value represents the difference between all three groups