Table 2.

Factors associated with vaccination during the antenatal period in eligible women at the time of birth

Variables	OR (95% CI)	P valuea	Adjusted OR (95% CI)	P valueb
Maternal age (y)	1.45 (1.18–1.80)	<.001	—	—
>40	Reference		Reference
30–40	0.96 (0.46–2.12)	.918	1.15 (0.48–3.01)	.751
<30	0.37 (0.15–0.90)	.025	0.49 (0.17–1.45)	.189
IMD score	0.72 (0.58–0.89)	.002	—	—
IMD quintile
First quintile	Reference		Reference
Second quintile	0.55 (0.23–1.28)	.168	0.65 (0.25–1.63)	.361
Third quintile	0.51 (0.25–1.06)	.066	0.66 (0.30–1.47)	.310
Fourth quintile	0.53 (0.26–1.10)	.085	0.71 (0.33–1.57)	.403
Fifth quintile	0.16 (0.05–0.46)	.001	0.10 (0.02–0.40)	.003
Self-reported ethnicity
White	Reference		Reference
Afro-Caribbean	0.24 (0.27–0.89)	.021	0.27 (0.06–0.85)	.044
Asian	0.49 (0.08–0.58)	.003	0.61 (0.31–1.16)	.147
Mixed	0.62 (0.30–1.20)	.171	1.01 (0.46–2.10)	.976
Not reported	1.09 (0.62–1.89)	.761	0.87 (0.45–1.65)	.688
Maternal BMI (kg/m2)	0.84 (0.67–1.04)	.127	—	—
Obesity (BMI ≥30 kg/m2)	0.55 (0.29–0.99)	.057	0.63 (0.31–1.22)	.184
Smoking at the time of birth	0.35 (0.02–2.01)	.333	—	—
Alcohol use at the time of birth	2.52 (0.10–63.9)	.515	—	—
Pregestational diabetes mellitus	5.19 (1.35–24.9)	.021	10.5 (1.74–83.2)	.014
Antenatal medication	1.47 (0.95–2.25)	.077	1.43 (0.84–2.41)	.176
Antenatal COVID-19	2.53 (0.30–21.2)	.356	1.62 (0.06–20.6)	.712
Gestational diabetes mellitus	1.16 (0.65–2.03)	.603	—	—

The overall vaccination uptake rate among those eligible was 28.5% (140/491).

BMI, body mass index; CI, confidence interval; IMD, index of multiple deprivation; OR, odds ratio.

Blakeway et al. COVID-19 vaccination during pregnancy. Am J Obstet Gynecol 2022.

^aUnivariable logistic regression

^bMultivariable logistic regression.