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. 2021 Aug 10;284:119881. doi: 10.1016/j.lfs.2021.119881

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Fig. 5 — Induced expression of integrin α5, and integrin αv in the lungs of SARS-CoV-2 infected K18-hACE2 mice and is inhibited by ATN-161 treatment. Integrin α5 (A–B), and Integrin αv (C–D) mRNA expression in lung at different time periods of ATN-161 by intravenous injection (i.v) after infection with SARS-CoV-2 (TCID50 = 2 × 10⁵ /0.05 mL) was determined by qRT-PCR. Data are presented as mean ± SEM. P values represent saline vs SARS-CoV-2 + vehicle and SARS-CoV-2 + vehicle vs SARS-CoV-2 + ATN-161 pooled, SARS-CoV-2 + ATN-161 responders, and SARS-CoV-2 + ATN-161 non-responders.