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Effect of ATN-161 on hepatic enzyme levels in the serum of SARS-CoV-2 infected K18-hACE2 mice. (A–B) aspartate aminotransferase (AST); (C–D) Alanine aminotransferase (ALT). Data are presented as mean ± SEM. P values represent saline vs SARS-CoV-2 + vehicle and SARS-CoV-2 + vehicle vs SARS-CoV-2 + ATN-161 pooled, SARS-CoV-2 + ATN-161 responders, and SARS-CoV-2 + ATN-161 non-responders.
