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. 2021 Aug 9;11:16116. doi: 10.1038/s41598-021-95238-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation analysis with adjustments for age and gender between FA values and neuropsychological/PSG indices in the RLS group. (A,B) FA values in the right anterior thalamic radiation were significantly associated with the composite score of attention/executive function, and visual memory. (C) FA values in the right inferior fronto-occipital fasciculus were negatively correlated with BAI. (D,E) FA values in the left corticospinal tract were negatively correlated with number of PLMs and MAI. Red colors indicate the portions of fiber tracts where FA values significantly correlated with neuropsychological/PSG indices. FA, fractional anisotropy; PSG, polysomnography; RLS, restless legs syndrome, BAI, Beck anxiety inventory; PLM, periodic leg movement; MAI, movement arousal index.