Table1.
Demographics and sleep characteristics of patients with RLS and controls.
| Patients (n = 30) | Controls (n = 31) | p | |
|---|---|---|---|
| Age | 46.3 ± 13.0 | 44.1 ± 12.0 | 0.482 |
| Men:women, no | 8:22 | 8:23 | 0.939 |
| Age at RLS onset (years) | 36.9 ± 14.1 | – | |
| RLS duration (years) | 9.4 ± 8.5 | – | |
| IRLS score | 29.9 ± 7.6 | – | |
| Previous RLS medication use, n (%) | 13 (43.3) | – | |
| Night polysomnography | (n = 15) | ||
| Time in bed (min) | 446.0 ± 46.7 | 450.4 ± 43.2 | 0.767 |
| Total sleep time (min) | 389.4 ± 45.8 | 404.4 ± 43.3 | 0.305 |
| Sleep latency (min) | 12.5 ± 16.3 | 10.8 ± 10.9 | 0.676 |
| Sleep efficiency (%) | 87.4 ± 5.6 | 89.9 ± 5.8 | 0.180 |
| Arousal index (h) | 17.6 ± 6.5 | 13.8 ± 5.3 | 0.044* |
| WASO (min) | 44.1 ± 22.5 | 35.1 ± 24.4 | 0.237 |
| N1 sleep (%) | 12.4 ± 6.3 | 11.9 ± 5.2 | 0.793 |
| N2 sleep (%) | 59.9 ± 11.4 | 56.8 ± 8.5 | 0.327 |
| N3 sleep (%) | 7.7 ± 5.1 | 8.5 ± 7.3 | 0.699 |
| REM sleep (%) | 20.1 ± 6.9 | 22.7 ± 4.2 | 0.189 |
| AHI/h | 4.0 ± 3.0 | 2.3 ± 3.0 | 0.084 |
| PLMI (h) | 16.2 ± 20.9 | 4.0 ± 5.8 | 0.005* |
| MAI (h) | 3.6 ± 4.3 | 1.0 ± 1.6 | 0.005* |
RLS, restless legs syndrome; IRLS, International Restless Legs Scale; WASO, wakefulness after sleep onset; REM, rapid eye movement; AHI, apnea–hypopnea index; PLMI, periodic leg movement index; MAI, movement arousal index.
*p < 0.05, independent t-tests for continuous variables and Fischer’s exact tests for categorical variables.