. 2021 Aug 9;12:4790. doi: 10.1038/s41467-021-25158-6

Table 3.

Gene essentiality results for (a) only metabolic genes (FBA and E[T]FL.cb) and (b) metabolic and expression genes (E[T]FL.cb) compared with experimental results.

(a)	FBA,E[T]FL.cb (metabolic genes)	Predictions
	MCC = 0.48	Essential	Nonessential
Experimental	Essential	53	106
Experimental	Nonessential	12	945
(b)	E[T]FL.cb (metabolic and expression genes)	Predictions
	MCC = 0.50	Essential	Nonessential
Experimental	Essential	72	118
Experimental	Nonessential	16	1132

Matthews correlation coefficient (MCC) was used as a metric to assess the quality of the predictions.