. Author manuscript; available in PMC: 2021 Nov 10.

Published in final edited form as: J Int Neuropsychol Soc. 2021 Feb 10;27(10):1048–1057. doi: 10.1017/S1355617721000059

Table 2.

Mean and standardized mean cognitive function scores by time-averaged LDL-C category using a generalized linear model.

		Average LDL-C levels over follow-up, mg/dL
	N	< 100	100 – 129	130-159	≥ 160	p-trend
Test		Mean test score (SD)^*
DSST (digits correctly substituted, 0-133)	3321	70.6 (16.8)	71.1 (16.6)	70.4 (15.6)	68.0 (15.1)	<0.001
RAVLT (words correctly recalled, 0-15)	3322	9.0 (2.0)	9.1 (1.9)	9.0 (1.9)	8.7 (1.9)	0.002
Stroop Test (seconds to correctly name colors + number of errors, 1-160)	3320	22.6 (11.8)	22.2 (10.5)	22.4 (9.8)	24.0 (12.1)	0.01

Test		Standardized Mean test score^* (SD)
DSST	3321	0.03 (1.05)	0.06 (1.03)	0.02 (0.97)	−0.14 (0.94)	<0.001
RAVLT	3322	0.02 (1.05)	0.05 (1.00)	0.03 (0.98)	−0.13 (1.00)	0.002
Stroop Test	3320	−0.01 (1.08)	−0.04 (0.96)	−0.03 (0.90)	0.11 (1.11)	0.01

Abbreviations: DSST, Digit Symbol Substitution Test; LDL-C, low-density lipoprotein-cholesterol; RAVLT, Rey Auditory Verbal Learning Test; SD, standard deviation

Lower mean and standardized mean scores indicate worse performance on the DSST and RAVLT tests, but better performance on the Stroop Test.