Table 3.
Subgroups analyses of normal systolic blood pressure with mortality.
| Systolic blood pressure, mmHg | ||||||
|---|---|---|---|---|---|---|
| Hazard ratios (95%CI), P-value | ||||||
| Characteristic | Number | 90–99 | 100–109 | 110–119 | 120–129 | P-interaction |
| All-cause mortality | ||||||
| Sex | 0.578 | |||||
| Male | 584 | 1.58(0.76,3.27)0.219 | 0.65(0.38,1.10)0.108 | 1.0 | 1.01(0.69,1.47)0.972 | |
| Female | 490 | 3.01(1.31,6.94)0.010 | 1.45(0.56,3.75)0.446 | 1.0 | 1.88(0.98,3.62)0.059 | |
| Race | 0.721 | |||||
| Non-white | 396 | 3.08(0.78,12.07)0.107 | 0.97(0.40,2.35)0.943 | 1.0 | 1.90(0.96,3.76)0.066 | |
| White | 678 | 1.89(1.03,3.45)0.039 | 0.91(0.53,1.56)0.732 | 1.0 | 1.27(0.91,1.77)0.157 | |
| Body mass index, kg/m2 | 0.560 | |||||
| <25 | 456 | 1.09(0.49,2.41)0.837 | 0.62(0.31,1.21)0.161 | 1.0 | 1.14(0.74,1.77)0.558 | |
| ≥25 | 618 | 3.12(1.46,6.68)0.003 | 1.14(0.53,2.45)0.744 | 1.0 | 1.52(1.01,2.28)0.046 | |
| Diabetes | 0.082 | |||||
| No | 913 | 2.23(1.22,4.08)0.009 | 0.84(0.46,1.52)0.564 | 1.0 | 1.45(1.04,2.03)0.029 | |
| Yes | 161 | 0.67(0.11,4.15)0.669 | 1.10(0.4,2.97)0.857 | 1.0 | 0.86(0.31,2.41)0.771 | |
| Cardiovascular mortality | ||||||
| Sex | 0.605 | |||||
| Male | 584 | 1.49(0.19,11.89)0.709 | 0.37(0.07,1.99)0.248 | 1.0 | 1.59(0.58,4.34)0.364 | |
| Female | 490 | 18.7(2.16,161.92)0.008 | 0.38(0.04,3.22)0.372 | 1.0 | 2.37(0.54,10.28)0.251 | |
| Race | 0.731 | |||||
| Non-white | 396 | 0.00 (0.00, Inf) 0.999 | 0.67(0.05,8.24)0.754 | 1.0 | 0.92(0.22,3.77)0.909 | |
| White | 678 | 4.81(1.05,22.09)0.043 | 0.47(0.09,2.53)0.381 | 1.0 | 2.52(0.96,6.58)0.059 | |
| Body mass index, kg/m2 | 0.012 | |||||
| <25 | 456 | 7.40(1.36,40.14)0.02 | 0.95(0.11,8.1)0.964 | 1.0 | 1.21(0.32,4.49)0.778 | |
| ≥25 | 618 | 1.15(0.11,12.33)0.908 | 0.00 (0.00, Inf) 0.997 | 1.0 | 2.93(1.19,7.21)0.019 | |
| Diabetes | 0.662 | |||||
| No | 913 | 6.31(1.56,25.5)0.01 | 0.57(0.11,2.96)0.506 | 1.0 | 2.25(0.93,5.44)0.073 | |
| Yes | 161 | 0.66(0.04,11.12)0.774 | 0.00 (0.00, Inf) 0.999 | 1.0 | 3.04(0.59,15.57)0.182 | |
CI, confidence interval.
When analyzing a subgroup variable, age, sex, race, marital status, education level, smoking, body mass index, diastolic blood pressure, total cholesterol, high density lipoprotein cholesterol, and comorbidities (diabetes, cardiovascular disease, and cancer) were all adjusted except the variable itself.