Table 1.
Pandemics since the middle ages.
| Years | Diseases | Reported region | Deaths |
|---|---|---|---|
| 1347–1351 | Bubonic Plague | Europe | Over 50 million |
| 1489 | Typhus | Europe | 17,000 |
| 1500s | Smallpox | Europe, Americas | 12–25 million in Mexico |
| 1510 | Influenza | Global | Unknown |
| 1557–1558 | Influenza | Europe | Unknown, 8,000 in London |
| 1580 | Influenza | Asia, Africa, Europe, America | Unknown, 8,000 deaths in Rome |
| 1635, 1656 | Measles | Britain, Europe | Unknown |
| 1700s | Yellow Fever | Americas, Europe, Africa | 10,000 deaths in Philadelphia |
| 1729–1730, 1732–1733, | Influenza | Global | 0.5 million |
| 1761–1762 | Influenza | Americas, Europe | Unknown |
| 1780–1782 | Influenza | China, India, Europe, America | Unknown |
| 1788–1790 | Influenza | Europe, North America | 0.8 million |
| 1800s | Cholera | Europe, Americas, Asia | 50–100 million |
| 1830–1831, 1832–1833 | Influenza | China, Russia, Europe | 0.9 million |
| 1889–1893 | Influenza/Russian Flu | Global | 1 million |
| 1918–1919 | Influenza/Spanish Flu | Global | 40–50 million |
| 1957–1958 | Influenza/Asian Flu | Global | 1–1.5 million |
| 1968 | Influenza/Hong Kong | Global | 0.75–1 million |
| 1979 | HIV/AIDS | Global | 35 million |
| 1977–1978 | Influenza/Russian Flu | Global | Unknown |
| 2009–2010 | Influenza/Swine Flu | Global | 284,500 |
| 2003 | SARS | Global | 774 |
| 2019 | COVID-19 | Global | 2.9 million |