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. 2021 Aug 5;148(15):dev199711. doi: 10.1242/dev.199711

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© 2021. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — Single-cell RNA-seq from the human developing spinal cord. (A) UMAP of CS12, CS14, CS17 and CS19 samples annotated by gene module score. (B) Stacked bar chart indicating the cell type composition per time point (colour key as in A). (C) UMAP of the combined human neural dataset coloured by gene module score. Colour and brightness of cells reflects the representative gene module (n=43,485). (D) Feature plots of markers of neural progenitors (SOX2), neurons (ELAVL3) and neural crest progenitors (SOX10) and neurons (SIX1). (E) Feature plots of the spinal cord progenitor UMAP showing the patterned expression of the indicated DV patterning markers.