Figure 4.

Enhanced M2Mϕ numbers by hAM-MSC-dressing therapy in vivo

(A–C) Representative immunohistolabeling images demonstrating that accumulation of CD206⁺ cells (green) in the remote, peri-infarct, and infarct regions of the myocardium at (A) 3 days, (B) 10 days, and (C) 28 days post-hAM-MSC-dressing therapy (hMSC-dressing group), in comparison with the ICM control group. Samples were counter stained with DAPI. The number of CD206⁺DAPI⁺ cells was counted and presented in the charts. At least 10 images per myocardial area were assessed per animal. Scale bars, 50 μm. Data are presented as mean value per heart. n = 4−6 hearts in each group. ∗p < 0.05 and ∗∗∗p < 0.001 versus ICM group. Student’s t test.