Table 3.

RNA and protein levels of Mtm1 (MTM1), Bin1 (BIN1), and Dnm2 (DNM2) in Mtm1^−/y, Bin1^mck−/−, Dnm2^SL/+ and Dnm2^RW/+ mice

Mouse line	RNA/protein	MTM1	BIN1	DNM2
Mtm1−/y	protein (WB)	absent	fold = 2	fold = 2.5
			p < 0.05	p < 0.001
		age 5 weeks	age 7 weeks	age 5 weeks
		Cowling et al.34	Lionello et al.39	Cowling et al.34
	RNA (qPCR)	fold = 0.5	N/D	fold = 1.3
		p = 0.0095		p < 0.05
		age 7 weeks		age 7 weeks
	RNA (transcriptomic)	fold = 0.2	fold = 1.4	fold = 1.02
		p = 1.98E−09	p = 0.046	p = 0.95
		age 7 weeks	age 7 weeks	age 7 weeks
Bin1mck−/−	protein (WB)	fold = 1.07	absent	fold = 1.5
		p = 0.95		p = 0.052
		age 8 weeks		age 8 weeks
				unpublished data
	RNA (qPCR)	fold = 0.97	absent	fold = 1.4
		p = 0.28	p = 0.0091	p < 0.05
		age 7 weeks	age 7 weeks	age 7 weeks
				unpublished data
	RNA (transcriptomic)	fold = 0.93	fold = 0.10	fold = 1.1
		p = 0.63	p = 1.63E−209	p = 0.42
		age 7 weeks	age 7 weeks	age 7 weeks
Dnm2SL/+	protein (WB)	fold = 0.7	fold = 0.95	fold = 2.2
		p = 0.016	p > 0.05	p = 0.057
		age 8 weeks	age 8 weeks	age 8 weeks
				Massana Muñoz et al.28
	RNA (qPCR)	fold = 1.2	N/D	fold = 0.9
		p = 0.15		p > 0.05
		age 7 weeks		age 7 weeks
				Massana Muñoz et al.28
	RNA (transcriptomic)	fold = 0.87	fold = 1.37	fold = 1.04
		p = 0.023	p = 2.34E−09	p = 0.77
		age 7 weeks	age 7 weeks	age 7 weeks
Dnm2RW/+	protein	fold = 1.2	fold = 1.8	fold = 1.05
		p = 0.4	p = 0.07	p = 0.6
		age 7 weeks	age 7 weeks	age 7 weeks

WB, western blot; N/D, not determined.