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. 2021 Jun 29;7(7):e07429. doi: 10.1016/j.heliyon.2021.e07429

Table 3.

Clinically relevant annotations enriched with genes interrupted by gentamicin (partial data).

GO ID GO Term Adjusted p-value Associated genes found
C0023264 Leigh syndrome 9.3E-04 DLAT, DLD, NDUFA10, NDUFA12, NDUFA2, NDUFA9, NDUFS4, NDUFS8, PDHA1, SDHA
C0751651 Mitochondrial diseases 1.7E-02 DLAT, DLD, NDUFA10, NDUFA12, NDUFA2, NDUFA9, NDUFB9, NDUFS1, NDUFS4, NDUFS6, NDUFS8, NDUFV1, NDUFV2, PDHA1, SDHA, SDHAF1, SDHD, SUCLA2, SUCLG1
C1838979 Mitochondrial complex I deficiency 2.0E-01 NDUFB9, NDUFS1, NDUFS4, NDUFS6, NDUFV1, NDUFV2
CN043648 Nonsyndromic hearing loss and deafness 1.0E+00 CLPP, MYH9, RDX
C0236038 Hereditary hearing loss and deafness 1.0E+00 CLPP, DLAT, DLD, MYH9, NDUFA10, NDUFA12, NDUFA2, NDUFA9, NDUFB9, NDUFS1, NDUFS4, NDUFS6, NDUFS8, NDUFV1, NDUFV2, NF2, PDHA1, RDX, SDHA, SDHAF1, SDHD, SUCLA2, SUCLG1

The raw p-values were adjusted using the Bonferroni step down method.