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. 2021 Jul 27;12:669605. doi: 10.3389/fgene.2021.669605

TABLE 1.

Comparison of baseline characteristics between dicycloplatin-sensitive and dicycloplatin-resistant patients.

Baseline characteristic Sensitive (n = 9) Resistant (n = 7) p value All patients (n = 16)
Age, median (range), years 66 (61–79) 63 (51–72) 0.210 66 (51–79)
Smoking history, no. (%) 0.633
Yes 4 (44.4) 2 (28.6) 6 (37.5)
No 5 (55.5) 5 (71.4) 10 (62.5)
Drinking history, no. (%) 0.596
Yes 2 (44.4) 3 (42.9) 6 (37.5)
No 7 (55.5) 4 (57.1) 10 (62.5)
Tumor stage at diagnosis, no. (%) 1
II 1 (11.1) 0 (0.0) 1 (6.3)
IV 8 (88.8) 7 (100.0) 15 (93.8)
Gleason sum at diagnosis, no. (%) 1
≤7 6 (66.6) 4 (57.1) 10 (62.5)
≥8 3 (33.3) 3 (42.9) 6 (37.5)
Prior treatment for PCa, no. (%)
Surgery 2 (22.2) 1 (14.3) 1 3 (18.8)
Radiotherapy 1 (11.1) 2 (28.6) 0.4 3 (18.8)
Chemotherapy 3 (33.3) 5 (71.4) 0.157 10 (62.5)
Endocrine therapy 2 (22.2) 7 (100.0) 0.003 9 (56.3)
Pretreatment PSA level, median (range), ng/ml 87.6 (9.9–775.6) 79.3 (2.9–800) 0.837 86.0 (2.9–800)
Pretreatment-free PSA level, median (range), ng/ml 14.0 (0.5–48.6) 10.8 (0.9–29.8) 0.681 11.2 (0.5–48.6)

PSA, prostate-specific antigen. p values are based on Fisher’ exact test and Mann–Whitney U test for categorical and continuous parameters, respectively.