TABLE 4.
Molecular network analysis using IPA.
| IPA | −Log (p value) | Ratio | z-score | Molecules |
|---|---|---|---|---|
| PI3K/AKT signaling | 1.72 | 0.0405 | 1.342 | AKT3, BCL2, CSF2RB, IL7R, ITGA2, ITGA3, and ITGB1 |
| NF-κB signaling | 0.556 | 0.0234 | 0 | AKT3, PDGFRA, TGFBR2, and TLR1 |
| LXR/RXR activation | 2.55 | 0.0583 | 2.449 | APOC1, APOE, C9, CD36, IL1RAP, MSR1, and NR1H3 |
| GNRH signaling | 0 | 0.0118 | 0 | ADCY8 and CACNA1G |
| Chemokine signaling | 0.47 | 0.026 | 0 | CAMK1 and CXCR4 |
| Atherosclerosis signaling | 1.38 | 0.0413 | 0 | APOC1, APOE, CD36, CXCR4, and MSR1 |