Table 4.
Multivariate logistic regression analysis to identify the less complex models.
| Model CLIN | Model CLIN-F | Model CLIN-COG | Model CLIN-COG-F | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Basic information | N (N with delirium) | 771 (181); 23.48% | 771 (181); 23.48 | 771 (181); 23.48 | 771 (181); 23.48% | ||||||
| Nagelkerke's pseudo-R2 | 0.242 | 0.256 | 0.304 | 0.313 | |||||||
| F | 30.41 | 29.09 | 30.14 | 28.78 | |||||||
| p | <0.001* | <0.001* | <0.001* | <.001* | |||||||
| AUC [95%-CI] | 0.760 [0.721–0.800] | 0.769 [0.731–0.808] | 0.798 [0.762–0.835] | 0.801 [0.765–0.838] | |||||||
| Variable | Categories | N ( N with delirium); Percentage | OR [95%-CI] | p | OR [95%-CI] | P | OR [95%-CI] | p | OR [95%-CI] | P | |
| Clinical | ASA | Score I + II | 215 (17); 7.91% | ||||||||
| Score III | 477 (116); 24.32% | 2.25 [1.24–4.24] | 0.009* | 2.09 [1.15–3.96] | 0.019* | 2.22 [1.20–4.28] | 0.013* | 2.08 [1.12–4.02] | 0.024* | ||
| Score IV | 79 (48); 60.76% | 7.75 [3.55–17.42] | <0.001* | 7.02 [3.19–15.90] | <0.001* | 6.98 [3.12–16.09] | <0.001* | 6.44 [2.86–14.93] | <0.001* | ||
| Multimorbidity | ≤4 diseases | 210 (26); 12.38% | |||||||||
| 5–8 diseases | 489 (126); 25.77% | 1.85 [1.13–3.09] | 0.016* | 1.83 [1.13–3.06] | 0.017* | 1.79 [1.08–3.04] | 0.027* | 1.77 [1.07–3.01] | 0.029* | ||
| ≥9 diseases | 72 (29); 40.28% | 3.61 [1.81–7.26] | <0.001* | 3.27 [1.62–6.64] | <0.001* | 3.36 [1.63–6.94] | 0.001* | 3.07 [1.48–6.40] | 0.003* | ||
| Cut-to-suture time | <90 min | 260 (41); 15.77% | |||||||||
| 90–180 min | 256 (38); 14.84% | 0.67 [0.38–1.15] | 0.145 | 0.62 [0.35–1.07] | 0.088(*) | 0.63 [0.35–1.11] | 0.114 | 0.59 [0.33–1.05] | 0.077(*) | ||
| >180 min | 255 (102); 40.00% | 1.69 [0.93–3.03] | 0.082(*) | 1.62 [0.89–2.93] | 0.112 | 1.69 [0.92–3.10] | 0.093(*) | 1.63 [0.88–3.01] | 0.120 | ||
| Renal failure | >45 mmol/ml | 672 (148); 22.02% | |||||||||
| <45 mmol/ml | 99 (33); 33.33% | 1.58 [0.94–2.61] | 0.080(*) | 1.46 [0.86–2.44] | 0.155 | 1.49 [0.87–2.53] | 0.139 | 1.40 [0.81–2.38] | 0.227 | ||
| Polypharmacy | ≤5 drugs | 339 (60); 17.70% | |||||||||
| 6–10 drugs | 338 (88); 26.04% | 1.18 [0.77–1.81] | 0.447 | 1.08 [0.70–1.66] | 0.743 | 1.03 [0.66–1.61] | 0.886 | 0.96 [0.61–1.51] | 0.866 | ||
| > 10 drugs | 94 (33); 35.11% | 1.66 [0.90–3.05] | 0.101 | 1.34 [0.71–2.51] | 0.358 | 1.37 [0.72–2.60] | 0.332 | 1.16 [0.59–2.22] | 0.666 | ||
| Cardio-pulmonary Bypass | No | 544 (90); 16.54% | |||||||||
| Yes | 227 (91); 40.09% | 1.45 [0.77–2.80] | 0.252 | 1.59 [0.84–3.10] | 0.159 | 1.54 [0.81–3.00] | 0.191 | 1.66 [0.87–3.26] | 0.129 | ||
| Surgery type | Ortho./Visc. | 464 (70); 15.09% | |||||||||
| Cardio-vasc. | 307 (111); 36.16% | 1.09 [0.56–2.07] | 0.804 | 1.26 [0.64–2.43] | 0.503 | 1.32 [0.67–2.54] | 0.420 | 1.49 [0.74–2.91] | 0.253 | ||
| Cognition | MoCA | ≥23 points | 517 (100); 19.34% | ||||||||
| <23 points | 254 (81); 31.89% | 1.95 [1.28–2.98] | 0.002* | 1.82 [1.19–2.80] | 0.006* | ||||||
| Digit span | ≥5 points | 460 (86); 18.70% | |||||||||
| <5 points | 311 (95); 30.55% | 1.50 [1.01–2.25] | 0.047* | 1.49 [0.99–2.24] | 0.053(*) | ||||||
| Pre-existing dementia | No | 761 (172); 22.60% | |||||||||
| Yes | 10 (9); 90.00% | 26.17 [4.49–498.64] | 0.003* | 28.35 [4.82–541.97] | 0.002* | ||||||
| Frailty | Clinical frailty score | Score 1–3 | 441 (89); 20.18% | ||||||||
| Score 4–8 | 330 (92); 27.89% | 1.88 [1.23–2.90] | 0.004* | 1.74 [1.12–2.72] | 0.015* | ||||||
Results from multivariate logistic regression analysis comparing four possible models with higher economical practicability. All the data were grouped into the categories stated. To ensure the possibility of statistical comparison of all models, only the patients were included, for whom data in all the models were available. Statistically significant tests results are highlighted in bold type, significant p-values are marked with *, and p-values at a significance level of .05 to 0.1 are marked with (*).