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. 2021 Jul 9;297(2):100948. doi: 10.1016/j.jbc.2021.100948

Figure 1.

Figure 1

SCARA1 recognizes the modified LDL and VLDL.A, schematic models of the SR-A family members. B, FACS data of the hSCARA1-transfected HEK293 cells incubated with AcLDL, OxLDL, or LDL. Mock represents nontransfected cells. C, confocal fluorescent images of the hSCARA1 (with GFP tag)-transfected HEK293 cells incubated with LDL, AcLDL, or OxLDL (the scale bar represents 25 μm). D, FACS data of the hSCARA1-transfected HEK293 cells incubated with AcVLDL, OxVLDL, or VLDL. E, confocal fluorescent images of the hSCARA1 (with GFP-tag)-transfected HEK293 cells incubated with VLDL or OxVLDL (the scale bar represents 25 μm). F, FACS data of the hSCARA1-transfected HEK293 cells incubated with AcHDL, OxHDL, or HDL. G, confocal fluorescent images of the hSCARA1 (with mCherry tag)-transfected cells incubated with HDL, AcHDL, or OxHDL (the scale bar represents 25 μm). AcHDL, acetylated HDL; AcVLDL, acetylated VLDL; HDL, high-density lipoprotein; LDL, low-density lipoprotein; OxHDL, oxidized HDL; OxVLDL, oxidized VLDL; VLDL, very-low-density lipoprotein.