Skip to main content
. 2021 Jul 9;297(2):100948. doi: 10.1016/j.jbc.2021.100948

Figure 2.

Figure 2

SCARA1 recognizes the modified LDL and VLDL through its C-terminal SRCR domain.A, FACS data of the full-length hSCARA1 or the hSCARA1ΔSRCR-transfected HEK293 cells incubated with LDL or AcLDL. B, FACS data of the full-length hSCARA1 or the hSCARA1ΔSRCR-transfected HEK293 cells incubated with LDL or OxLDL. C, ELISA data of the interactions between the CL-SRCR fragment (homotrimer) and the SRCR domain (monomer) of hSCARA1 with the unmodified LDL or the modified LDL in the presence of Ca2+ (2 mM). D, ELISA data of the interactions between the CL-SRCR fragment of hSCARA1 with the unmodified VLDL and the modified VLDL in the presence of Ca2+ (2 mM). GFP was applied as a negative control. ELISA data are representative of three repeated experiments and presented as the mean ± SD. AcLDL, acetylated LDL; CL, collagen-like; LDL, low-density lipoprotein; OxLDL, oxidized LDL; SRCR, scavenger receptor cysteine-rich; VLDL, very-low-density lipoprotein.