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. 2021 Aug 9;4(8):e2119110. doi: 10.1001/jamanetworkopen.2021.19110

Table 4. Multivariable Regression for Empathy and Career Regret at End of Medical School Among US Medical Students Who Completed the AAMC Y2Q and AAMC GQ .

Variables reported at year 2 (Y2Q) Empathy at year 4 (GQ) Career regret at year 4 (GQ)
Coefficient (95% CI) P value Overall P value Odds Ratio (95% CI) P value Overall P value
No. of mistreatments
0 1 [Reference] NA .86 1 [Reference] NA <.001
1 0.01 (−0.112 0.15) .83 1.35 (1.12 to 1.63) .002
>1 −0.03 (−0.17 to 0.11) .67 1.87 (1.56 to 2.23) <.001
MSLES subscale (for each 1 point higher)
Faculty interactions 0.02 (0.02 to 0.05) NA .04 1.02 (0.99 to 1.05) NA .32
Emotional climate −0.02 (−0.05 to 0.01) NA .08 1.02 (0.98 to 1.05) NA .38
Student-student interactions 0 (−0.02 to 0.02) NA .86 0.97 (0.95 to 1.00) NA .04
Burnouta
Disengagement (for each 1-point increase) −0.03 (−0.06 to −0.004) NA .03 1.15 (1.11 to 1.20) NA <.001
Exhaustion (for each 1-point increase) 0.01 (−0.01 to 0.03) NA .22 1.07 (1.04 to 1.09) NA <.001
Empathy (for each 1-point increase)b 0.63 (0.62 to 0.65) NA <.001 0.98 (0.96 to 1.00) NA .03
Overall QOL (for each 1-point increase)c 0.02 (−0.01 to 0.0) NA .22 0.95 (0.90 to 0.99) NA .02
Stress (for each 1-point increase)d 0.01 (−0.01 to 0.04) NA .28 1.01 (0.97 to 1.04) NA .71
Career regret NA NA NA 5.71 (4.60 to 7.10) NA <.001
Sex
Female 0.74 (0.63 to 0.85) NA <.001 1.00 (0.98 to 1.03) NA .82
Male 1 [Reference] NA 1 [Reference] NA
Age (for each year older) 0.05 (0.03 to 0.07) NA <.001 1.00 (0.97 to 1.02) NA .82
Marital status
Single 1 [Reference] NA .85 1 [Reference] NA .90
Legally married 0.01 (−0.13 to 0.14) .94 1.11 (0.92 to 1.34) .28
Common law or civil union 0.1 (−0.73 to 0.93) .81 1.44 (0.51 to 4.07) .49
Divorced 0.01 (−0.56 to 0.57) .98 1.00 (0.45 to 2.25) >.99
Separated, but still legally married 0.64 (−0.59 to 1.87) .31 1.25 (0.26 to 5.99) .78
Widowed 2.02 (−2.13 to 6.16) .34 NA NA
No. of dependents
0 1 [Reference] NA .91 1 [Reference] NA .33
1 −0.05 (−0.31 to 0.20) .69 1.19 (0.85 to 1.66) .31
2 or more −0.04 (−0.35 to 0.27) .79 0.82 (0.52 to 1.29) .39

Abbreviations: AAMC, American Association of Medical Colleges; GQ, Graduation Questionnaire; MSLES, Medical School Learning Environment Survey; NA, not applicable; QOL, quality of life; Y2Q, Medical School Year 2 Questionnaire.

a

As measured by a modified version of the Oldenburg Burnout Inventory (see Methods). Score ranges 8 to 32 for exhaustion and 5 to 20 for disengagement, with higher scores indicating higher levels of burnout.

b

As measured by the Interpersonal Reactivity Index scale. Scores range from 0 to 32, with higher scores indicating higher levels of empathy.

c

As measured by the single-item linear analogue QOL scale. Scores range from 0 to 10, with higher scores indicating better overall quality of life.

d

As measured by a 4-item Perceived Stress Scale. Scores range from 0 to 16, higher scores indicating higher perceived levels of stress.