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. 2021 Jul 26;22(4):1059. doi: 10.3892/etm.2021.10493

Figure 4.

Figure 4

ROCK1 is a direct target of miR-139-5p. TargetScan predicted that ROCK1 was a direct downstream target of miR-139-5p. (A) Putative ROCK1 binding site on miR-139-5p (ROCK1-WT). (B) 293T cells were co-transfected with NC mimics or miR-139-5p mimics with ROCK1-WT or ROCK1-MUT. **P<0.01 vs. miR-NC. ROCK1, Rho-associated kinase 1; miR, microRNA; WT, wild-type; MUT, mutant; NC, negative control.