Morphological and Cytophysiological Changes in the Adult Rat Adrenal Medulla after Prenatal and Postnatal Exposure to Endocrine-Disrupting DDT

. 2020;12(2):50–54. doi: 10.17691/stm2020.12.2.06

Morphological parameters of the adrenal glands of mature rats in the control group and rats exposed to low doses of DDT at various stages of ontogenesis (M±m)

Parameters	control group	Prenatal and postnatal exposure to DDT	Postnatal exposure to DDT
The area of the medulla (μm²)	812,000.00±8315.22	598,200.00±45,313.12*	757,000.00±41,000.00^#
The total area of chromaffin cells in the medulla section (μm²)	578,850.00±21,767.91	394,938.00±46,496.07*	544,700.00±19,100.00^#
The area of the chromaffin cell (μm²)	108.39±1.97	112.32±4.40	99.99±3.25*^#

* Statistically significant differences from the values of the control group; ^# differences between the group with “postnatal exposure to DDT” and the group with “prenatal and postnatal exposure to DDT”.