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. 2021 Aug 5;15:3425–3441. doi: 10.2147/DDDT.S315060

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© 2021 Zhang et al.

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CSS attenuated the depressive-like behaviors in CUMS model. (A) Experimental timeline of CSS for antidepressant treatment. The behavioral tests were started after the last exposure of CUMS procedure. Mice were sequentially subjected to (B) body weight, (C) SPT, (D) TST, and (E) FST. Data are expressed by mean ± SEM. *p < 0.05 means a significant difference.