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. 2021 Aug 5;15:3425–3441. doi: 10.2147/DDDT.S315060

Table 2.

The Detailed Information of Potential Active Ingredients in CSS Against MDD

Mol ID Compounds Degree MW OB (%) Caco-2 BBB DL Herbs
MOL000098 Quercetin 18 302.25 46.43 0.05 −0.77 0.28 Bupleurum falcatum L.; Cyperus rotundus L.; Glycyrrhiza uralensis Fisch.;
MOL000422 Kaempferol 9 286.25 41.88 0.26 −0.55 0.24 Bupleurum falcatum L.; Cyperus rotundus L.; Paeonia lactiflora Pall.; Glycyrrhiza uralensis Fisch.;
MOL000006 Luteolin 8 286.25 36.16 0.19 −0.84 0.25 Cyperus rotundus L.;

Abbreviations: MW, molecular weight; OB, oral bioavailability; Caco-2, Caco-2 permeability; BBB, blood-brain barrier; DL, drug-likeness.