Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic of amino acid flux by SLC7A5/SLC3A2 in ER+ breast cancer cells. The bidirectional amino acid transporter, SLC7A5, interacts with SLC3A2 and SLC1A5 on the plasma membrane. In ER+ breast cancer cells, leucine uptake by SLC7A5 accelerates cell proliferation. The glutamine cycle model supports the view that high consumption of glutamine, due to the activation of SLC7A5, is retrieved by SLC1A5
