FIGURE 3.

Signal regulatory protein α (SIRPα) expression was associated with tumor‐infiltrating immune cells in esophageal squamous cell carcinoma (ESCC). A‐D, Representative immunohistochemical staining of SIRPα (A), CD80 (B), CD163 (C), and CD8 (D) in a surgically resected specimen from one patient with ESCC. All of the images represent a single area of one specimen. Scale bar = 50 μm. E, F, Association between SIRPα expression and the infiltrating numbers of tumor immune cells including CD80 (E), CD163 (F), and CD8 (G) were evaluated by manual cell counts of immunohistochemically stained samples. *P < .001; **P = .03