TABLE 1.
Baseline characteristics of 131 esophageal squamous cell carcinoma patients grouped according to expression of signal regulatory protein alpha (SIRPα)
| Factor | Category | High SIRPα (n = 84) | Low SIRPα (n = 47) | P value |
|---|---|---|---|---|
| Age, years | 66.4 (±0.9) | 65.7 (±1.2) | .6700 | |
| Sex | Male | 72 (86) | 40 (85) | .9200 |
| Tumor location | Ce | 11 (13) | 9 (19) | .5100 |
| Ut | 14 (17) | 7 (15) | ||
| Mt | 41 (49) | 21 (45) | ||
| Lt | 18 (21) | 10 (21) | ||
| Histopathology | Well differentiated | 25 (30) | 6 (13) | .0600 |
| Moderately differentiated | 49 (58) | 36 (77) | ||
| Poorly differentiated | 10 (12) | 5 (11) | ||
| pT | T2‐4 | 64 (76) | 23 (49) | .0017 |
| pN | N1‐3 | 31 (37) | 17 (36) | .9300 |
| pM | M1 | 0 (0) | 0 (0) | |
| pStage | Stages II‐III | 64 (76) | 27 (57) | .0270 |
| Preoperative treatment | None | 20 (24) | 15 (32) | .2800 |
| NAC | 27 (32) | 19 (40) | ||
| NACRT | 31 (37) | 10 (21) | ||
| dCRT | 6 (7.1) | 3 (6.4) | ||
| Effects of preoperative treatment | Grade 1 | 45 (69) | 23 (74) | .7800 |
| Grade 2 | 12 (18) | 4 (13) | ||
| Grade 3 | 8 (12) | 4 (13) |
Data are shown as mean (±SD) or n (%).
Abbreviations: Ce, cervical esophagus; dCRT, definitive chemoradiotherapy; Lt, lower thoracic esophagus; Mt, middle thoracic esophagus; NAC, neoadjuvant chemotherapy; NACRT, neoadjuvant chemoradiotherapy; pM, pathological metastasis; pN, pathological lymph node metastasis; pStage, pathological stage; pT, pathological depth of tumor invasion; Ut, upper thoracic esophagus.